The Best Hypochlorous Acid Sprays of 2025

Jun 24, 2025

Whether it’s a new sheet mask or using an unexpected item as a spot treatment, it can often feel like there’s a new must-have skin care product being raved about on social media every other day. And most of the time, experts will tell you the hype isn’t all it’s cracked up to be. But recently, beauty-obsessed TikTokers have been touting their love for hypochlorous acid spray as a complexion saviour — and many dermatologists agree that it really can be an effective tool in your skin care arsenal.

To learn more about hypochlorous acid sprays — including what they are, what they do and which ones are worth your money — I turned to experts who have experience with them. Check out what they had to say below.

Selected.

Best overall

Briotech Topical Skin Spray

$16.99

Amazon

Learn more

Best splurge

Tower 28 SOS Daily Rescue Facial Spray

$28.00

Amazon

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Best travel size

Avenova Cleanser Spray

$29.99

$29.99

Amazon

Learn more

Long before it was used as a skin care product, hypochlorous acid spray was used in clinical settings thanks to its antimicrobial, anti-inflammatory, and tissue-safe properties, says Dr. Anetta Reszko, a board-certified dermatologist in New York. “It also happens to be a naturally occurring molecule produced by the body’s white blood cells as part of the immune response and plays a key role in defending against infection by targeting harmful bacteria, viruses, and other pathogens.”

More recently, hypochlorous acid spray has become a popular skin care product because its antibacterial, antiviral, and anti-inflammatory properties can help combat several skin issues, like acne, eczema, sunburns and more. “It soothes reactive or inflamed skin, relieves itching, and supports healing, all while being gentle enough for daily use, says Reszko. “And because it mimics a substance your body already produces, it’s well-tolerated, non-drying, and won’t lead to antibiotic resistance like some prescription treatments can.”

When shopping for a hypochlorous acid spray to use on your face, experts recommend prioritizing the following criteria:

To come up with the list of best hypochlorous acid sprays, I looked for options that meet the criteria given by our experts and that have at least a 4-star average rating from hundreds of reviews.

Tower 28, which makes one of our favorite lip balms, has one of the most popular hypochlorous acid sprays on the market. The acid calms irritated skin, while the 4.5 pH balance helps to keep your skin barrier strong. This spray can be used morning and night and should be used in place of toner before moisturizing.

This spray can be used on the body, face or even eyelids and can help soothe eczema flare-ups or generally irritated skin. The formula is free of fragrances and preservatives, making it a good option for sensitive skin users. It has a 4.6-star average rating from 10,854 reviews on Amazon and comes in various sizes.

This hypochlorous acid spray has a 150 ppm and can either be spritzed on skin or applied to a cotton ball and then applied. Reviewers say it’s helped them with irritation, dry eyes, tattoo healing and more.

“The spray is considered very gentle, pure with its .01% concentration, and widely recommended across dermatologic and ophthalmologic use cases (i.e., eyelid dermatitis and perioral dermatitis),” says Reszko. “The product is safe near the eyes (ophthalmology-grade) and appropriate for sensitive skin.” One thing to note: At .68 ounces, it’s the smallest bottle on our list.

This spray, which has a 4.7-star average rating from over 1,000 reviews on Amazon, has a .015% concentration and a 5.5 pH balance, so it shouldn’t irritate sensitive skin. Also helpful: The formula is hypoallergenic and noncomedogenic to prevent breakouts from sprouting up.

At NBC Select, we work with experts with specialized knowledge and authority based on relevant training and experience. We also ensure all expert advice and recommendations are made independently and without undisclosed financial conflicts of interest.

Bethany Heitman is a contributor at NBC Select and a journalist who regularly covers topics like beauty, home and lifestyle.

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Bethany Heitman is a contributing editor at NBC Select.